Monday, November 01, 2010

Pharma high



Or high profit would be more accurate
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It is the world's oldest euphoric drug – and quite recently the first medicine made from cannabis was licensed in the UK.
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Sativex, a tincture of extracts from the cannabis plant, is sprayed under the tongue up to 12 times a day, as a treatment for the stiffness and spasticity associated with multiple sclerosis.
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But it is not going to be popping up on the black market as Britain's latest dance drug.
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The Home Office has rated it as having zero abuse potential.
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Britain is the first country to give the drug full regulatory approval, although it has had a limited licence to treat neuropathic pain in Canada since 2005.
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It is made from plants grown at a secret location in southern England by GW Pharmaceuticals, a small biotech company whose shares have risen 60 per cent in the last six months in anticipation of yesterday's announcement.
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The medicinal benefits of cannabis have been known for at least 2,000 years.
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Its analgesic properties were described by the British herbalist Nicholas Culpeper in 1653.
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Two drugs containing a synthetic form of the active constituent tetrahydrocannabinol (THC) were used in the UK for more than 30 years to treat nausea in cancer patients undergoing chemotherapy.
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There are at least 60 active constituents of cannabis and scientists believe they can harness them to alleviate a range of symptoms.
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Millions of pounds are being invested by drug companies to test medicines derived from the plant as treatments for pain, epilepsy and inflammatory conditions such as bowel and skin diseases.
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As cannabis is a natural plant, neither it nor the oil produced from it can be patented.
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Drug companies are therefore developing unique combinations of the constituents or finding a unique means of delivering them to the body, which would be patentable.
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The plants grown by GW Pharmaceuticals are of two strains bred to deliver high levels of cannabidiol (CBD) and THC, which are then mixed together.
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THC is the constituent which produces feelings of euphoria, but the levels are too low to make patients high and the effect is counteracted by the cannabidiol.
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Professor Richard Langford, consultant in anaesthesia and pain medicine at Barts and The London NHS Trust, who was involved in the trials of Sativex, said: The blood levels of THC when people smoke cannabis rise to a huge peak.
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By contrast, with the spray the rise is tiny.
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GW Pharmaceuticals appeared to be on the brink of winning a licence for Sativex by 2005.
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But UK regulatory authorities wanted more evidence of its efficacy as a treatment for multiple sclerosis.
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That meant a further trial and more delay.
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The drug is being marketed in Britain by the German company Bayer and is priced at £125 for a 10ml vial, which works out at £11 a day for a "typical" patient, according to the company.
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But it does not work for everyone.
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About one in 10 of the 100,000 patients with multiple sclerosis will be eligible for the drug, of whom only half are expected to benefit.
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The Multiple Sclerosis Society said it was worried a postcode lottery could develop if primary care trusts differed on whether to pay for it.
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We welcome the benefits it can bring but we want to see it made available to anyone who needs it, a spokeswoman for the society said.
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By Jeremy Laurance, Health Editor
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Eleven pounds per day for a typical patient they say

Anybody could get the real thing for much less and probably find it more effective and a lot more enjoyable than some spray under the tongue

No contest

Unfortunately one is legal the other is still not in most places

Who wins?

Why pharma high!

4 comments:

How to buy Pain killer said...

Chronic pain is a treatment that involves a lot of patience and strength, and that is the direct struggle with painkillers such as hydrocodone, vicodin, norco, and add some of them is xanax to combat anxiety that they produce painkillers.

Anonymous said...

Cannabis is illegal, alcohol for sale everywhere, although far more dangerous, and not only for yourself, just read the newspapers... murders, (domestic) violence against women, children...

If alcohol would be discovered right now, it would be classified as dangerous as f.i. LSD, and thus illegal.

... food for thought ?

ps : not only marihuana can be used as a natural product, also opium, even cocaine, would do; if not "marketed differently" already, ...profits assured...

Anonymous said...

cocaine is not really a natural product, sorry about this, coca leaves are

Anonymous said...

"the real thing" now sometimes contains up to 20 % of thc, dangerous, and...modified ofcourse...
and is to be considered as a hard drug in my humble opinion

WHY ? faster harvesting makes more profit, most marihuana on the market is grown under lamps, which is not a bliss for electricityconsumption, thus not exactly environmentalfriendly + lots of ( toxic ) waists, if not grown organicly